Bioinformatics
× Genetic Engineering

Turning biological data into scalable insights

About Me

What if DNA isn’t just biology,but nature’s most elegant technology?

That idea is what pulled me into bioinformatics. I’m fascinated by how information is encoded, regulated, and expressed within living systems and how we can read, model, and even redesign those processes using computation. With a background in genetic engineering, I’ve spent time both at the bench and behind the screen, understanding how biological data is generated and how it can be interpreted at scale. I work at the intersection of biology and computation to explore patterns in biological data and to build end to end systems that make those patterns easier to understand and use. What excites me most is the possibility of treating biology not just as something to observe, but as something to engineer, optimize, and translate into real world impact whether that’s in health, research, or emerging biotechnologies.

Projects

Genome QC & Annotation Pipeline

Snakemake • assembly validation • synteny analysis • annotation error detection (mChlEAn)

Genetic Algorithm Pipeline

Optimized pipeline using ML • Flask API • Angular frontend

View Analysis Report →

Metabolomics ML Pipeline

Workflow design • PLS-DA • biomarker discovery • ML models (KNN, SVM, Random Forest)

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Variant Parser (Python)

VCF/BCF parsing & variant extraction using BCFtools and Picard

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NGS I

End-to-end RNA-seq: QC • alignment • differential expression • SNP/INDEL calling • HPC

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NGS II (Genome Assembly)

De novo • hybrid (DBG2OLC, MaSuRCA, HybridSPAdes) • long-read (Canu, FALCON) • short-read (SOAPdenovo2, Velvet, IDBA) • k-mer analysis

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Metagenomic Analysis

QIIME2 • DADA2 denoising • phylogenetic & taxonomic analysis in R

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Structural proteomics

Blast • UniProt • PDB • SWISS-MODEL • PyMOL

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Genome visualisation Tool

Java • FASTA/GTF parsing • exon visualization • sequence stats

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Database Design

VCF parser • SQLite • REST API • variant querying • density analysis

In Silico Drug Analysis (SARS-CoV-2)

AutoDock & PyRx docking • ADME profiling

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Skills

Wet Lab

Molecular Techniques (I & II), Immunology Lab, Microbial Genetics Lab, Cytogenetics Lab, Recombinant DNA Technology, Enzyme Engineering, Gene Expression, Animal Cell Culture, Plant Genetic Engineering, Bioseparation Engineering

Dry Lab

Data Domains:

Genomics, Transcriptomics, Proteomics, Metabolomics, Epigenetics, Metagenomics, NGS

Tech Stack:

Python, R, Java, SQL (SQLite), Bash, Machine Learning, REST APIs, Node.js, Express.js, JavaScript

Experience

Bioinformatician (Contract)

Unilever • England, UK

GA-based optimization • ML modeling • Flask REST API • Angular frontend • end-to-end pipeline

Junior Technician

Chennai • India

Pedigree analysis • mutation visualization • genomic data interpretation • ethical data handling

Senior Teacher

Remote

Top 15% educator • mentoring • communication • student engagement

Bioengineering Club

SRM university

Committee Head & Event Coordinator • team leadership • DNA workshop (300+) • microscopy challenge • outreach impact

Volunteer for rare disease day

SRM university

Awareness campaigns • community outreach • event coordination

Publication

2019 Novel Coronavirus: A Review on Epidemiology, Pathophysiology, Diagnosis and Current Clinical Trials in Vaccine Development

Bentham Science Publishers • 2020

View Publication →

Contact

dnalabz@arpanpardeshi.com

arpan.pardeshi1999@gmail.com

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